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European equity markets traded sharply lower on Wednesday, reversing the previous session’s gains, as trade tensions intensified following the implementation of new US tariffs, including a cumulative 104% levy on Chinese imports. The STOXX 50 fell 2.6% and the broader STOXX 600 shed 2.5%, erasing roughly 2% in gains from Tuesday. Losses were broad-based, with all sectors in negative territory. Pharmaceuticals, oil & gas, basic resources, and real estate led the declines. Meanwhile, the European Commission is considering retaliatory tariffs of up to 25% on a wide range of US exports valued at approximately €22.1 billion. European Commission President Ursula von der Leyen spoke with Chinese Premier Li Qiang on Tuesday, offering a "negotiated resolution" to what she described as "the widespread disruption caused by the US tariffs". On the corporate front, major companies were sharply lower, including Novo Nordisk (-5.7%), SAP (-1.9%), LVMH (-3%), Nestle (-1.6%) and ASML Holding (-2.5%).